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. Author manuscript; available in PMC: 2012 Apr 13.
Published in final edited form as: Dev Cell. 2010 Apr 20;18(4):533–543. doi: 10.1016/j.devcel.2010.02.013

Figure 6. NEBD requires high levels of CyclinB1-Cdk1 activity.

Figure 6

HeLa cells co-expressing the CyclinB1-Cdk1 biosensor and Cdk1AF-mCherry. Three cells entering M phase-like states without cytokinesis are displayed. Low CyclinB1-Cdk1 activity, visualised by a weak increase in FRET activity, is sufficient to trigger cell rounding up (cell A and the two first M phase-like states of cell C) but higher levels are required for NEBD (cell B and third M phase-like state of cell C).