Fig. 2.

Dynamic and reciprocal interactions between the infarcted myocardium and the engineered cardiac patch. (1) Infiltrating cells will interact with the delivered cells via direct contact and/or secreted molecules. (2) Degradation products of the scaffold or matrix containing the cells will interact with the host tissue cells and infiltrating cells. (3) The repair cells will also interact with the healthy and necrotic myocardial tissue at the infarct site. Created using Servier Medical Art.