Fig. 2.
X expression and autosomal expression in large protein complexes versus others. For each tissue, we computed the ratio of the median of X gene expression of large complexes (≥ 7 proteins, n = 59) and the median of X gene expression of other protein complexes (< 7 proteins, n = 52), which we called the XL/XO ratio (red). Both categories have been defined from results presented in Fig. 1B. The ratio of the median of autosomal gene expression of large complexes (n = 696) and the median of autosomal gene expression of other protein complexes (n = 151)—the AL/AO ratio (blue)—was computed similarly. Error bars have been obtained by bootstrapping protein complexes and computing both ratios and represent 95% bootstrap confidence interval. We pooled the data for eight tissues (see text) and computed the median and confidence interval the same way. The two green dashed lines indicate expectations with a twofold increase of expression (ratio of 2) and without any change in expression (ratio of 1).