Table 2.
Comparison of PTCH1 between two forms of Esophageal Cancer and precancerous lesions.
| PTCH1 Positive | PTCH1 Negative | p-value | |
|---|---|---|---|
| N (%) | N (%) | ||
| Adenocarcinoma | 27(96%) | 1 (4%) | |
| ESCC (Cancer tissue samples) | 39(38%) | 64(62%) | <0.0001a |
| ESCC (Normal tissue samples) | 0 (0%) | 103 (100%) | <0.0001a |
| PTCH1 Positive | PTCH1 Negative | p-value | |
| N (%) | N (%) | ||
| Squamous dysplasia | 5 (21%) | 19(79%) | 0.01b |
| Barrett’s Esophagus | 11(58%) | 8 (42%) | |
| PTCH1 Positive | PTCH1 Negative | p-value | |
| N (%) | N (%) | ||
| Squamous dysplasia | |||
| Mild/ moderate | 0 (0) | 12(100%) | |
| Severe/ carcinoma in situ | 5 (42%) | 7 (58%) | 0.04c |
| ESCC | 39(38%) | 64(62%) | 0.008c |
a
p-value based on the chi-square or Fisher’s exact test in comparison with adenocarcinoma;
b
p-value based on the chi-square or Fisher’s exact test;
c
p-value in comparison with Pre-ESCC mild/moderate based on Fisher’s exact test.