Table 1.
IC50 Table
| MCF-7 | MCF-7/DoxoR | Loewe interaction index | SK-BR-3 | SK-BR-3/NOdoxo | MDA-MB-231 | MDA-MB-231/DoxoR | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 (μM) | R sq | IC50 (μM) | R sq | MCF_7 | MCF-7/DoxoR | IC50 (μM) | R sq | IC50 (μM) | R sq | IC50 (μM) | R sq | IC50 (μM) | R sq | |
| Doxorubicin | 0,04 | 0,96 | 10 | 0,96 | antagonist | n.c. | 10 | 0,95 | 50 | 0,97 | 5 | 0,95 | 75 | 0,94 |
| Rottlerin | 0,005 | 0,96 | n.c. | n.c. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | ||
IC50 Table. IC50s of 24 h drug-treated MCF-7 and MCF-7/DoxoR cells. Data obtained were in luminescence units and analyzed with Graphpad Prism software, n.c. not convergent, n.d. not done.