Table 3.

Virological responses in the study by Manns et al. [34]

Groups	Overall SVR	SVR at end of follow-up	SVR by genotype
			GT 1	GT 2/3	GT 4/5/6
Higher-dose peg-IFN + Rib	65% P < 0.001	54% P = 0.01	42%	82%	50%
Lower-dose peg-IFN + Rib	56%, P = 0.41	47% P = 0.73	34%	80%	33%
IFN + Rib	54%	47%	33%	79%	38%

INF = Interferon, Rib = Ribavirin, SVR = sustained virologic response, GT = genotype. *P values are calculated for comparison with IFN + Rib