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. Author manuscript; available in PMC: 2012 Apr 16.
Published in final edited form as: Cell Cycle. 2009 Mar 18;8(5):765–772. doi: 10.4161/cc.8.5.7879

Figure 1. Novel Aurora kinase inhibitors identified by high throughput screening.

Figure 1

The chemical structure and the preferential conformations of the identified eight most potent hits are presented. The inhibitory efficiency (percent of inhibition) towards the kinase domain of Aurora A for each hit at 15 μm and 1.5 μM are also shown.