Table 3. TDT analysis for 12 SNPs in and around BMP4 in Maryland trios.
SNP name | Position | Minor allele | MAF (%) | FAM* | T | NT | OR (95%CI) | P Value | relative difference ratio |
rs17563 | 54417522 | 1 | 47.7 | 36 | 26 | 24 | 1.08 (0.62, 1.89) | 0.7789 | - |
s2071047 | 54418411 | 1 | 43.5 | 37 | 25 | 24 | 1.04 (0.60, 1.82) | 0.8817 | 5.23 |
rs2761880 | 54418986 | 1 | 3.9 | 5 | 4 | 2 | 2.00 (0.37, 10.92) | 0.4178 | 85.39 |
rs10130587 | 54419110 | 1 | 40.8 | 33 | 23 | 22 | 1.05 (0.58, 1.88) | 0.8837 | - |
rs2855532 | 54419965 | 1 | 46.1 | 38 | 19 | 33 | 0.58 (0.33, 1.01) | 0.0515 | −7.21 |
rs2761884 | 54421052 | 1 | 43.7 | 38 | 22 | 31 | 0.71 (0.41, 1.23) | 0.2188 | −3.07 |
rs2855530 | 54421917 | 2 | 48.1 | 41 | 35 | 24 | 1.46 (0.87, 2.45) | 0.1530 | - |
rs2738265 | 54422399 | 2 | 45.1 | 35 | 20 | 29 | 0.69 (0.39, 1.22) | 0.1954 | −6.62 |
rs762643 | 54422767 | 1 | 41.0 | 35 | 18 | 30 | 0.60 (0.33, 1.08) | 0.0833 | −1.41 |
rs762642 | 54423053 | 2 | 39.3 | 39 | 36 | 21 | 1.71 (1.00, 2.94) | 0.0469 | 9.24 |
rs2761887 | 54425052 | 2 | 44.7 | 33 | 18 | 28 | 0.64 (0.36, 1.16) | 0.1442 | −3.71 |
rs2032423 | 54425147 | 1 | 45.1 | 37 | 22 | 28 | 0.79 (0.45, 1.37) | 0.3994 | −4.88 |
FAM*: number of informative families.
T: number of transmitted alleles, NT: number of un-transmitted alleles.
Relative difference ratio: Relative difference ratio for MAFs between Asian and Maryland parents.