Figure 7. Spontaneous activities, APD₅₀ and mRNA expression in LV from 1-, 2- and 3-month WT and DCM mice.

A. Frequencies of spontaneous contractions after 3 Hz field stimulation in normal Krebs solution. (n = 9–14) B. APD₅₀ values in LVs from mice at 1, 2 and 3 months (data are averages of 7–14 hearts). ○▵: WT; •▴: DCM. C. Comparison of mRNA expression in LVs at 1- (n = 5) 2- (n = 7) and 3-months (n = 7). The expression levels of each gene are expressed relative to the average in WT LV at 2 month. Data are means ± SEM. *P<0.05, **P<0.01 between WT and DCM at the same age.