Skip to main content
. 2012 Apr 13;7(4):e33247. doi: 10.1371/journal.pone.0033247

Figure 4. Representative western blot images of nNOS and DRD2 protein expression in the MPOA (A) and the PVN (C) following three weeks of antipsychotic drug administration.

Figure 4

The calculated ODs of nNOS (B) and DRD2 (D) protein bands were normalized to each β-tubulin OD and expressed as a ratio. nNOS protien in the MPOA but not the PVN was significantly decreased by haloperidol. Haloperidol and risperidone increased DRD2 protien expression in both the MPOA and the PVN. Lanes: 1 = Vehicle; 2 = haloperidol; 3 = risperdone; 4 = quetiapine. Data are means ± s.e.means and expressed in arbitrary units. *p<0.05 vs Vehicle; **p<0.001 vs Vehicle.