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WT and JNK1 −/− mice were challenged with 5×108 pfu of adenovirus expressing IL-17A for 3 days (A–C) (N = 8, 7) or 1 µg of recombinant IL-17A for 24 hours (D–F)(N = 6, 7). A – inflammatory cells in BAL fluid. B, C, D, E – inflammatory cytokines in lung homogenate. F – antimicrobial peptide expression in lung tissue. * p<0.05, # p<0.10, nd – not detected.
