Table 1. Oral cancer-free survival (OCFS) analysis of risk factors in transformation of oral leukoplakia.
Characteristic | Malignant events/n | OCFS rate at 3 yr (SE) | OCFS rate at 5 yr (SE) | P |
All patients | 57/320 | 0.866 (0.024) | 0.820 (0.029) | |
Gender | 0.141 | |||
Female | 37/175 | 0.865 (0.032) | 0.814 (0.039) | |
Male | 20/145 | 0.867 (0.037) | 0.830 (0.044) | |
Age (yr) | 0.021 | |||
< = 60 | 38/228 | 0.880 (0.027) | 0.849 (0.031) | |
>60 | 19/92 | 0.827 (0.052) | 0.726 (0.071) | |
Lesion site | <0.001 | |||
Other sites | 19/199 | 0.920 (0.024) | 0.880 (0.032) | |
Lateral/ventral tongue | 38/121 | 0.789 (0.046) | 0.735 (0.052) | |
Lesion type | 0.001 | |||
Homogenous | 49/301 | 0.877 (0.024) | 0.842 (0.029) | |
Non-homogenous | 8/19 | 0.697 (0.116) | 0.542 (0.132) | |
Epithelial dysplasia | <0.001 | |||
Low grade | 27/229 | 0.937 (0.020) | 0.905 (0.026) | |
High grade | 30/91 | 0.675 (0.065) | 0.590 (0.073) | |
Smoking | 0.423 | |||
Never | 33/194 | 0.868 (0.031) | 0.816 (0.039) | |
Past and present | 11/86 | 0.888 (0.044) | 0.888 (0.044) | |
Unknown | 13/40 | |||
Alcohol intake | 0.689 | |||
Never | 32/196 | 0.875 (0.031) | 0.835 (0.037) | |
Past and present | 12/84 | 0.876 (0.045) | 0.847 (0.052) | |
Unknown | 13/40 |
SE, standard error of the mean.