Circular dichroism analysis of GCSF samples. The near-UV CD spectra are presented from Neupogen® (green), Neupogen22 (pink), heat-treated Neupogen® (yellow), or recombinant GCSF samples generated in Feb 2008 (light blue), Oct 2007 (purple), May 2007 (gray), Feb 2006 (navy), or Feb 2004 (red)