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Hydroxyl radical footprinting of IFN samples. Each set of bars represents one peptide from recombinant IFN samples generated in 2005 (red), 2004 (blue), two samples from Oct 2007 (green and gray), and Jan 2005 (purple). The y-axis represents the average number of oxidation events per peptide in the sample. Error bars 2 SD from a triplicate set of FPOP oxidations and analyses. Asterisks peptides with oxidation levels that significantly different than IFN 2005 (p ≤ 0.01)
