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. 2012 Feb 17;14(2):176–186. doi: 10.1208/s12248-012-9327-8

Fig. 2.

Fig. 2

Outcome of predicted power study in six nonlinear mixed-effects models at varying sample size per study arm from stochastic simulation and estimation method (grey squares), stochastic simulation and estimation method (black triangles) calibrated with type I error rate (dark red diamond) and MCMP method (grey circle)