Skip to main content
. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: J Invest Dermatol. 2012 Feb 16;132(5):1354–1362. doi: 10.1038/jid.2012.4

Table 4.

Odds ratios (and 95% CIs) of NMSC, BCC, and SCC according to ERCC6 haplotypes (rs2228527, rs4838518, rs2228529).

Haplotype Frequency
case/control
NMSC
OR (95% CI)
Frequency
BCC cases
BCC
OR (95% CI)
Frequency
SCC cases
SCC
OR (95% CI)
AGA
AAA
AAG
GGA
GAG
50.3/52.0
28.2/29.0
0.1/0.1
0.4/0.3
20.9/18.5
1.0 (referent)
1.11 (0.87 – 1.41)
1.28 (0.09 – 17.73)
1.88 (0.35 – 10.14)
1.63 (1.23 – 2.16)
49.3
29.0
  0.1
  0.4
21.0
1.0 (referent)
1.24 (0.94 – 1.63)
1.60 (0.12 – 21.80)
2.08 (0.35 – 12.28)
1.94 (1.40 – 2.67)
50.7
27.1
  0
  0.5
21.7
1.00 (referent)
0.94 (0.59 – 1.49)
--
0.71 (0.05 – 10.74)
1.07 (0.64 – 1.80)
Overall
p-value
    0.03     <0.01     0.99

Abbreviations: CI, confidence interval; OR, Odds ratio

All models were adjusted for the first three principle components, and baseline age, education, body mass index, and smoking

Six of the possible eight haplotypes were observed, with one occurring only among controls (GAA, n = 2)

Numbers do not add to 100 due to rounding