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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Kidney Int. 2012 Jan 18;81(9):856–864. doi: 10.1038/ki.2011.467

Figure 2. Proteinuria and BUN.

Figure 2

HIV-Tg mice were treated with vehicle, Am580, roflumilast (Rof) or Rof+Am580 from age of 4 weeks to 9 weeks. Serum was used for the determination of BUN (A) and urine was measured for albumin and creatinine to calculate the albumin/creatinine (Cr) ratio (mg/mg) (B). A significant difference in BUN and albumin/Cr ratio was detected among the groups by ANOVA (n=10). Pair-wise comparison with Bonferroni correction revealed significant difference between HIV-Tg+ Vehicle vs. all other groups (*p< 0.0001); HIV-Tg+Rof+Am580 vs HIV-Tg+Rof (**p<0.001); and HIV-Tg+Rof+Am580 vs HIV-Tg+Am580 (**p<0.001).