Table 3.

Motor Nerve Function by Change in Homocysteine

	Stay Normal (n = 205)	High to Normal (n = 94)	Normal to High (n = 19)	Stay High (n = 196)	p Value
Compound motor action potential (mV)
Baseline	6.8 ± 3.2	6.4 ± 3.1	6.4 ± 3.8	6.4 ± 3.3	.63
3 y	4.1 ± 2.8	4.2 ± 3.4	4.4 ± 3.8	3.7 ± 2.7	.70
6 y	3.8 ± 2.4	4.1 ± 2.6	3.7 ± 2.8	3.8 ± 2.2	.92
Nerve conduction velocity (m/s)
Baseline	45.1 ± 4.1	44.4 ± 3.5	42.4 ± 4.7*	44.0 ± 3.8†	.004
3 y	44.5 ± 4.2	44.3 ± 4.9	41.8 ± 4.2*	42.6 ± 4.7†,‡	.001
6 y	40.4 ± 3.8	39.6 ± 3.9	36.9 ± 5.3*	39.2 ± 3.8†,§	.001

Notes: p < .05 for * = Normal to High versus Stay Normal; † = Stay High versus Stay Normal; ‡ = Stay High versus High to Normal; § = Stay High versus Normal to High; high homocysteine = ≥13 μmol/L.