Figure 3.

Tau and Aβ measurements in non-contusional versus pericontusional groups. (A) Mean tau levels during the initial 24 h of microdialysis sampling were higher in patients with catheters placed in pericontusional regions: Error bars represent median and 25–75th percentiles (**P = 0.005, Mann–Whitney U-test). (B) Mean Aβ levels during the initial 24 h of microdialysis sampling were lower in pericontusional group (**P = 0.0012). (C) Tau levels decreased with time in all patients (*P = 0.0078 for non-contusional group, P = 0.016 for pericontusional group, Wilcoxon paired rank tests). (D) Aβ levels rose over time in all but one non-contusional patient (P = 0.29) and all but one pericontusional patient (*P = 0.031). NS = not significant.