Fig. 7.

The average kidney function (latent variable) score for each group of animals in the various models. The age groups include the 4-month AL group of rats, 8-month AL group of rats, 12-month AL group of rats, 18-month AL group of rats, 24-month AL group of rats, and the 24-month CR group of rats (24-CR). Kidney function score did not change much with age in the AL group until 24 months when it decreased to less than 50% of previous values. With the exception of model 5, the function score in the 24-month-old CR rats (24+CR) was similar to that observed in younger AL rats.