Table 3. Gene-based rank correlation of Swedish AD with other GWAS.
Sample | Disease/Trait | genes in model | t (p-value) | variance explained (r2) |
---|---|---|---|---|
Li et al. 2008 | AD | 13067 | 5.33 (9.9 × 10−8) | 0.0022 |
Reiman et al. 2007 | AD | 12872 | 2.63 (8.5 × 10−3) | 0.0005 |
Lambert et al. 2009 | AD | 13043 | 2.38 (1.7 × 10−2) | 0.0004 |
Kathiresan et al. 2009 | Triglycerides | 12734 | 4.16 (3.2 × 10−5) | 0.0014 |
Kathiresan et al. 2009 | HDL | 12712 | −0.26 (0.80) | NA |
Kathiresan et al. 2009 | LDL | 12734 | −1.0 (0.32) | NA |
UK Crohn (Barret et al. 2008) | Crohn disease | 12593 | 0.86 (0.39) | NA |
NJ Crohn (Barret et al. 2008) | Crohn disease | 12592 | 0.49 (0.62) | NA |
BE Crohn (Barret et al. 2008) | Crohn disease | 12592 | 1.55 (0.12) | NA |
Correlation was established using simple linear regression and the maximum number of ranked genes that were shared across each pair of GWAS. NA, not applicable.