Table 2.

Measurement differences of RF-IVUS data derived from different methods of analysis

	Analyses I versus*
	Analyses II	Analysis III
	Intra-observer re-analysis based on complete data set of all frames	Reduced number of frames (and potentially more difficult analysis)
Vessel geometry
∆ Vessel volume (mm3)	−0.98 ± 0.90	−0.04 ± 0.70
	P = 0.3	P = 1.0
∆ Lumen volume (mm3)	−1.07 ± 0.55	−0.48 ± 0.66
	P = 0.1	P = 0.5
∆ Plaque volume (mm3)	0.10 ± 0.90	0.44 ± 0.74
	P = 0.9	P = 0.6
∆ Plaque burden (%)	0.06 ± 0.41	−0.01 ± 0.46
	P = 0.9	P = 1.0
Plaque composition
∆ Fibrous volume (mm3)	0.32 ± 0.42	0.05 ± 0.42
	P = 0.5	P = 0.9
∆ Fibrous volume (%)	−0.23 ± 0.37	−0.63 ± 0.38
	P = 0.5	P = 0.1
∆ Fibro-lipidic volume (mm3)	−0.01 ± 0.19	0.08 ± 0.15
	P = 1.0	P = 0.6
∆ Fibro-lipidic volume (%)	−0.35 ± 0.22	−0.03 ± 0.22
	P = 0.1	P = 0.9
∆ Necrotic core volume (mm3)	0.28 ± 0.16	0.15 ± 0.16
	P = 0.1	P = 0.4
∆ Necrotic core volume (%)	0.34 ± 0.17	0.03 ± 0.24
	P = 0.1	P = 0.9
∆ Calcium volume (mm3)	0.09 ± 0.08	0.14 ± 0.08
	P = 0.3	P = 0.1
∆ Calcium volume (%)	0.24 ± 0.43	0.62 ± 0.37
	P = 0.6	P = 0.1

Values are normalized to 10 mm length; * 2-sided student t test; mean ± standard error of the mean