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. 2001 May 8;98(10):5637–5642. doi: 10.1073/pnas.101135498

Figure 5.

Figure 5

Misexpression of NeurΔRF anterior to the furrow inhibits eye disc growth and lateral inhibition. (A–D) SEM of ey-Gal4; 2xUAS-neur (A, C) and ey-Gal4; 2xUAS-neurΔRF; (B, D) adult eyes. (E–K) Expression of cell-type specific markers in ey-Gal4/+ (E, H, J), ey-Gal4; 2xUAS-neurΔRF (F, I, K), or Su(H) (G) discs. (E–G) Expression of Elav; misexpression of NeurΔRF results in an extremely small retinal field that displays neural hypertrophy (F), similar to the phenotype of Su(H) (G). (H, I) Expression of Ato; resolution of Ato to single R8 cells is incomplete after misexpression of NeurΔRF. A row that has resolved to single Ato-expressing cells in wild-type (H, arrows) maintains Ato in clusters of ≈3 cells (I, arrows) following misexpression of NeurΔRF. (J, K) Expression of Boss; multiple Boss-positive cells are observed in many ommatidia following misexpression of NeurΔRF.