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. 2011 Nov 30;13(6):R122. doi: 10.1186/bcr3068

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Copyright ©2011 Kashiwagi et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Survival of patients with triple-negative breast cancer based on E-cadherin and Ki67 expression. (A) TNBC with reduced E-cadherin expression showed a significantly worse overall survival time (P = 0.0054), and cases with Ki67 expression showed significantly worse overall survival time (P = 0.0181). Patients with E-cadherin-negative and Ki67-positive expression showed a significantly worse overall survival time (P = 0.001). (B) The prognosis of the E-cadherin-negative cancer patients was significantly poorer than that of the E-cadherin-positive cancer patients in regard to overall survival (P = 0.0058) in Stage II. The prognosis of the combination of E-cadherin-negative and Ki67-positive expression cancer patients was significantly poorer than that of the combination of E-cadherin-positive and Ki67-negative expression cancer patients in regard to overall survival and in Stage II (P = 0.0376).