Table 2.
Univariate and multivariate analysis with respect to overall survival in 190 triple-negative breast cancers
| Univarite analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Parameters | Odds ratio | 95% CI | P-value | Odds ratio | 95% CI | P-value |
| Regimen Anthracyclin-base vs 5FU-base |
0.38 | 0.13 to 1.08 | 0.068 | 0.46 | 0.15 to 1.38 | 0.164 |
| E-cadherin | ||||||
| Negative vs Positive | 0.25 | 0.09 to 0.72 | 0.010 | 0.26 | 0.09 to 0.76 | 0.013 |
| Ki67 | ||||||
| Negative vs Positive | 2.38 | 1.14 to 4.99 | 0.022 | 2.11 | 0.96 to 4.63 | 0.062 |
| E-cadherin (-) and Ki67 (+) | ||||||
| Negative vs Positive | 3.03 | 1.54 to 5.98 | 0.001 | 2.78 | 1.38 to 5.60 | 0.004 |
| p53 | ||||||
| Negative vs Positive | 1.60 | 0.75 to 3.42 | 0.229 | 1.13 | 0.51 to 2.52 | 0.758 |
| Stage | ||||||
| 1 vs 2, 3, 4 | 2.54 | 1.04 to 6.22 | 0.041 | 0.30 | 0.05 to 2.00 | 0.214 |
| Tumor size | ||||||
| ≤ 2 cm vs > 2 cm | 2.46 | 1.11 to 5.45 | 0.027 | 3.25 | 0.75 to 14.15 | 0.116 |
| Lymph node status | ||||||
| N0 vs N1, N2, N3 | 3.40 | 1.68 to 6.91 | 0.001 | 3.46 | 1.38 to 8.66 | 0.008 |
| Lymph-vascular invasion | ||||||
| Negative vs Positive | 1.84 | 0.94 to 3.58 | 0.074 | 1.36 | 0.68 to 2.74 | 0.390 |
| Nuclear grade | ||||||
| 1, 2, vs 3 | 2.36 | 1.07 to 5.21 | 0.034 | 1.93 | 0.58 to 6.39 | 0.282 |