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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Peptides. 2012 Feb 2;34(2):380–388. doi: 10.1016/j.peptides.2012.01.020

Figure 6. Ang-(1-7) reduces COX-2 and PGES gene expression in cardiac fibroblasts.

Figure 6

Cardiac fibroblasts were pre-treated with 100 nM Ang-(1-7) for 4 h and incubated with or without 10 nM ET-1 for increasing periods of time, as indicated. COX-2 mRNA (in Panel A) or PGES mRNA (in Panel B) were measured by RT real-time PCR. n = 5. For COX-2 mRNA in Panel A, ** denotes p < 0.005 compared to Ang-(1-7) or Ang-(1-7) and ET-1 treatment; for PGES mRNA in Panel B, * denotes p < 0.05 compared to Ang-(1-7) or Ang-(1-7) and ET-1 treatment.