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. 2012 Mar 13;106(8):1386–1394. doi: 10.1038/bjc.2012.70

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Copyright © 2012 Cancer Research UK

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Interaction of PI3K and MEK inhibitor combinations. Median effect analysis (CalcuSyn software) was used to evaluate the interaction between the inhibitor combinations shown in Figure 1. Points represent the mean of three independent experiments±standard error. Horizontal dotted lines indicate the boundaries for each interaction classification.