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. 2012 Apr 10;106(8):1406–1414. doi: 10.1038/bjc.2012.103

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Copyright © 2012 Cancer Research UK

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Differential regulation of EGFR ligands AREG and EREG by Ctx in Ctx-responsive and Ctx-resistant SCC cells. AREG- and EREG-specific ELISAs were used to quantitatively assess the effects of Ctx treatment (48 h) in Ctx-responsive A431 parental cells (A) and in two independent Ctx-resistant A431 pooled populations (B). Results are means (columns) and 95% confidence intervals (bars) of two independent experiments made in duplicate. Statistically significant differences (one-factor ANOVA analysis) between Ctx-untreated and Ctx-treated cells and/or between A431 parental cells and their Ctx-unresponsive pooled populations are shown.