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. 2012 Mar 27;106(8):1367–1373. doi: 10.1038/bjc.2012.85

Table 3. Statistical correlations between clinicopathological, immunohistochemical and molecular data for all tumours.

  Histological grade Ductal form Nuclear grade Mitosis Lymph node + Vascular invasion
HR− 0.080a 0.024a NS 0.091a NS NS
EGFR+ 0.061 0.083 NS 0.013 0.088 NS
αIGF1R+ 0.001 NS 0.07 0.004 NS 0.005
PTEN loss 0.065 NS NS NS NS 0.047
PIK3CA mut NS NS 0.043 NS NS NS
pAkt+ NS NS NS NS NS NS
pBad+ 0.001 NS 0.008 0.002 NS 0.006
mTOR+ NS NS 0.034 NS 0.12 NS
MAPK+ 0.029a NS NS NS NS NS
Ki67 >20% 0.087 NS NS 0.021 NS 0.082
p53 >10% NS NS 0.009 0.076 NS NS
p27+(nuclear) NS NS NS NS NS NS

Abbreviations: EGFR=epidermal growth factor 1-receptor; HR=hormonal receptors; IGF1R=insulin-like growth factor 1-receptor; MAPK=mitogen-activated protein kinase; NS=non-significant; PTEN=phosphatase and tensin homologue.

a

Inverse relationship.