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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Am J Transplant. 2011 Nov 9;12(3):590–599. doi: 10.1111/j.1600-6143.2011.03847.x

Figure 3. iNKT cells do not require CD1d to expand in the presence of alloreactive T cells.

Figure 3

The requirements of iNKT cell-CD1d interactions were investigated by generating CD1d−/− stimulators and confirming that TEa T cells lacked CD1d molecules by flow cytometry (A). iNKT cells were co-cultured with TEa T cells and stimulators that either express CD1d or are deficient in CD1d and proliferation determined after 3 days of culture (B). Data is presented as the mean of triplicate cultures ± s.d. of one experiment. *p=<0.05. Data is representative of 2 independent experiments.