Table 1.
Characteristics of the Patients
| Characteristic | Immediate ART Arm (N=405) |
Early ART Arm (N=401) |
All Patients (N=806) |
|---|---|---|---|
| Continent – no. (%) | |||
| Africa | 275 (68) | 279 (70) | 554 (69) |
| Asia | 29 (7) | 23 (6) | 52 (6) |
| North America | 21 (5) | 18 (4) | 39 (5) |
| South America | 80 (20) | 81 (20) | 161 (20) |
| Gender | |||
| Male – no. (%) | 266 (66) | 235 (59) | 501 (62) |
| Median (IQR) age at enrollment (yr) | 34 (29, 40) | 34 (29, 42) | 34 (29, 41) |
| Tuberculosis – no. (%) | |||
| Confirmed | 193 (48) | 181 (45) | 374 (46) |
| Probable | 208 (51) | 218 (54) | 426 (53) |
| Not TB | 4 (1) | 2 (1) | 6 (1) |
| Median (IQR) CD4 Count (cells/mm3) |
70 (34, 146) |
82 (40, 144) |
77 (36, 145) |
| Median (IQR) HIV-1 RNA (log10 copies/mL) |
5.39 (4.94, 5.79) |
5.50 (5.03, 5.79) |
5.43 (5.00, 5.79) |
| Prior AIDS diagnosis – no. (%) | 26 (6) | 29 (7) | 55 (7) |
| Median (IQR) Body Mass Index (kg/m2) |
19.1 (17.3, 21.1) |
19.4 (17.7, 21.8) |
19.2 (17.5, 21.4) |
| Initial ART Regimen – no. (%*) | |||
| EFV, TDF, FTC | 394 (98) | 368 (97) | 762 (97) |
| Median (IQR) days of tuberculosis therapy at time of ART start | 10 (7, 12) | 70 (66, 75) | 14 (10, 70) |
*
Percentage based on number of subjects who started ART in this study.