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. Author manuscript; available in PMC: 2012 Apr 20.
Published in final edited form as: N Engl J Med. 2011 Oct 20;365(16):1482–1491. doi: 10.1056/NEJMoa1013607

Table 2.

Proportions of AIDS or Death at 48 weeks




Study Population
Immediate
ART Arm
Early
ART
Arm
N Proportion with
AIDS or death
by 48 weeks
95% CI for
Difference in
Proportions
P Value
All Patients 806 12.9% 16.1% (−1.8%, 8.1%) 0.45*
Within CD4 Stratum:
   < 50 cells/mm3 285 15.5% 26.6% (1.5%, 20.5%) 0.02
   ≥ 50 cells/mm3 521 11.5% 10.3% (−6.7%, 4.3%) 0.67
Subsets:
  Confirmed TB at Entry 374 13.8% 19.7% (−1.8%, 13.6%) 0.21*
  Within CD4 Stratum:
   < 50 cells/mm3 151 17.9% 31.4% (−0.4%, 27.3%) 0.06
   ≥ 50 cells/mm3 223 10.8% 12.1% (−7.3%, 9.8%) 0.77
  Suspected TB at Entry 432 15.4% 19.7% (−3.0%, 11.7%) 0.35*
  Within CD4 Stratum:
   < 50 cells/mm3 134 14.1% 30.5% (2.5%, 30.4%) 0.02
   ≥ 50 cells/mm3 298 15.9% 14.5% (−9.8%, 7.1%) 0.75
  Low BMI (≤18.5 kg/m2) at Entry 332 16.3% 26.5% (1.2%, 19.2%) 0.06*
  Within CD4 Stratum:
   < 50 cells/mm3 130 15.2% 38.2% (8.0%, 37.8%) 0.003
   ≥ 50 cells/mm3 202 16.9% 17.8% (−9.9%, 11.6%) 0.88
*

Stratified by CD4 stratum