TABLE 2.
HIV disease and medical characteristics of the study samples
| Young
|
Old
|
p | Pairwise comparisons | |||
|---|---|---|---|---|---|---|
| HIV− (n = 59) | HIV+ (n = 53) | HIV− (n = 54) | HIV+ (n = 88) | |||
| Hepatitis C (%) | 3 | 4 | 17 | 34 | <.001 | O+ > O− > Y+, Y− |
| Hypertension (%) | 2 | 9 | 22 | 30 | <.001 | O+ > Y+, Y− |
| Hypercholesterolemia (%) | 0 | 2 | 15 | 19 | <.001 | O+, O− > Y+, Y− |
| Diabetes mellitus (%) | 0 | 2 | 7 | 10 | .031 | O+ > Y− |
| HIV disease characteristics | ||||||
| HIV duration (years)a | — | 6.9 (5.2) | — | 15.3 (7.4) | <.001 | O+ > Y+ |
| AIDS (%) | — | 25 | — | 64 | <.001 | O+ > Y+ |
| cART (%) | — | 70 | — | 81 | .222 | — |
| Nadir CD4b (cells/μl) | — | 265 (204, 356) | — | 123 (40, 300) | <.001 | O+ < Y+ |
| Current CD4b (cells/μl) | — | 559 (404, 840) | — | 512 (308, 738) | .182 | — |
| Detectable plasma HIV RNA (%) | — | 40 | — | 24 | .058 | — |
| Detectable CSF HIV RNAc (%) | — | 28 | — | 16 | .176 | — |
Note. Y− = younger HIV seronegative; O− = older HIV seronegative; Y+ = younger HIV seropositive; O+ = older HIV seropositive; CD4 = cluster of differentiation 4; CSF = cerebrospinal fluid; cART = combination antiretroviral therapy.
a
Data represent means with standard deviations in parentheses.
b
Data represent medians with interquartile ranges in parentheses.
c
O+, n = 56; Y+, n = 36.