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. Author manuscript; available in PMC: 2012 Apr 16.
Published in final edited form as: Am J Physiol Cell Physiol. 2008 Mar 19;294(5):C1169–C1174. doi: 10.1152/ajpcell.00096.2008

Fig. 5.

Fig. 5

ATP-induced activation of cyclin D1 protein expression in VSMC is mediated by TCF-4 and PKA. A: time course of cyclin D1 protein expression in response to 30 μM ATP as assessed by Western blotting with cyclin D1 antibodies. B and C: VSMC were transduced with control adenovirus or with Ad-PKI (B) or with Ad-dnTCF-4 (C). Cells were stimulated with 30 μM ATP for 12 h, and cell lysates were analyzed by Western blotting with antibodies against cyclin D1 and β-actin. The densitometry of selected blots is shown as % of maximal response to ATP.