Table 1.
Country | No. of studies | Age range (mean)a |
Years of diagnosisa | iPLEX |
GWAS |
Combined |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cases | Controls | Cases | Controls | Total | Cases | Controls | Total | Cases | Controls | Total | |||
U.S.A | 5 | 25 - 92 (52) | 24 - 92 (62) | 1990 - 2010 | 711 | 448 | 1159 | 35 | 1126 | 1161 | 746 | 1574 | 2320 |
Australia | 3 | 25 - 91 (56) | 29 - 72 (46) | 1990 - 2009 | 186 | 59 | 245 | 21 | 657 | 678 | 207 | 716 | 923 |
U.K. | 5 | 22 - 93 (45) | 42 - 81 (53) | 1971 - 2010 | 573 | 111 | 684 | 6 | 1374 | 1380 | 579 | 1485 | 2064 |
Finland | 3 | 27 - 90 (55) | 18 - 80 (57) | 1990 - 2004 | 101 | 88 | 189 | 85 | 221 | 306 | 186 | 309 | 495 |
Germany | 6 | 22 - 88 (57) | 24 - 81 (58) | 1993 - 2008 | 740 | 501 | 1241 | 126 | 215 | 341 | 866 | 716 | 1582 |
Greece | 1 | 21 - 79 (53) | 34 - 82 (50) | 1997 - 2010 | 273 | 85 | 358 | 0 | 0 | 0 | 273 | 85 | 358 |
Netherlands | 1 | 26 - 62 (39) | NA | 1995 - 2007 | 67 | 0 | 67 | 0 | 0 | 0 | 67 | 0 | 67 |
Sweden | 1 | 48 - 88 (62) | 48 - 85 (62) | 1998 - 2000 | 27 | 26 | 53 | 0 | 0 | 0 | 27 | 26 | 53 |
Total | 25 | 21 - 93 (52) | 18 - 92 (56) | 1971 - 2010 | 2707 | 1385 | 4092 | 273 | 3593 | 3866 | 2980 | 4978 | 7958 |
Study-specific distributions shown in Supplementary Table 1