Table 1.
Pathological changes in the CNS
Cells | Meningeal infiltration | Perivascular infiltration | Choroid plexus infiltration | Hydrocephalus | Axonal degenerationa |
---|---|---|---|---|---|
BWα−β− | 0/5 (0)b | 0/5 (0) | 0/5 (0) | 0/5 (0) | 0/1 (0) |
8a-1Am | 3/3 (100) | 2/3 (66) | 2/3 (66) | 2/3 (66) | NA |
8a-1Ae | 5/5 (100) | 0/5 (0) | 0/5 (0) | 1/5 (20) | 1/1 (100) |
8a-1A3 | 4/4 (100) | 0/4 (0) | 1/4 (25) | 0/4 (0) | NA |
8a-1A1 | 4/9 (44) | 1/9 (11) | 0/9 (0) | 0/9 (0) | 0/4 (0) |
8b-1C5 | 5/10 (50) | 0/10 (0) | 0/10 (0) | 0/10 (0) | 2/3 (66) |
8b-1Cs | 4/5 (80) | 3/5 (60) | 0/5 (0) | 1/5 (20) | 1/1 (100) |
8b-1CZ | 4/4 (100) | 2/4 (50) | 1/4 (25) | 1/4 (25) | 0/1 (0) |
NA not assayed
Assayed via SMI 311 immunostain
Number of mice affected/total number of mice examined (percent affected)