Table 2.

Resting brain metabolism and perfusion summary table. Abbreviations: PD‐ND = Parkinson's disease subjects without dementia; PD‐MCI = Parkinson's disease diagnosed with mild cognitive impairment; PDD = Parkinson's disease and dementia; AD = Alzheimer's disease; PET = positron emission tomography; SPECT = single photon emission computed tomography.

Regional resting brain metabolism and perfusion	PD‐ND < controls	PD‐MCI < controls or PD‐no MCI	PDD < controls	PDD < PD‐ND	AD vs. PDD
Frontal lobe	(46) (PET) (58) (PET) (3) (SPECT) (43) (SPECT)	(34) (PET) (72) (SPECT)	(58) (PET) (70) (PET) (3) (SPECT) (62) (SPECT) (43) (SPECT)	(58) (PET) (74) (PET)	(43) (SPECT) (AD < PDD)
Temporal lobe	(32) (PET) (58) (PET) (39) (SPECT)	(72) (SPECT)	(58) (PET) (70) (PET) (3) (SPECT) (62) (SPECT) (43) (SPECT)	(58) (PET) (74) (PET)	(70) (PET) (AD < PDD) (43) (SPECT) (AD < PDD)
Parietal lobe	(32) (PET) (58) (PET) (2) (SPECT) (43) (SPECT)	(72) (SPECT)	(58) (PET) (70) (PET) (3) (SPECT) (62) (SPECT) (26) (SPECT) (43) (SPECT) (67) (SPECT)	(58) (PET) (43) (SPECT)	(43) (SPECT) (AD < PDD)
Basal Ganglia	(46) (PET) (58) (PET) (43) (SPECT)		(58) (PET)
Cerebellum	(58) (PET)	(34) (PET) (PD‐MCI > controls)	(58) (PET)
Occipital lobe	(58) (PET) (2) (SPECT)		(58) (PET) (43) (SPECT)	(43) (SPECT)	(70) (PET) (AD > PDD)
Brainstem		(34) (PET) (PD‐MCI > controls)
Hippocampus	(46) (PET)