Table 2.
Resting brain metabolism and perfusion summary table. Abbreviations: PD‐ND = Parkinson's disease subjects without dementia; PD‐MCI = Parkinson's disease diagnosed with mild cognitive impairment; PDD = Parkinson's disease and dementia; AD = Alzheimer's disease; PET = positron emission tomography; SPECT = single photon emission computed tomography.
| Regional resting brain metabolism and perfusion | PD‐ND < controls | PD‐MCI < controls or PD‐no MCI | PDD < controls | PDD < PD‐ND | AD vs. PDD |
|---|---|---|---|---|---|
| Frontal lobe | (46) (PET) (58) (PET) (3) (SPECT) (43) (SPECT) | (34) (PET) (72) (SPECT) | (58) (PET) (70) (PET) (3) (SPECT) (62) (SPECT) (43) (SPECT) | (58) (PET) (74) (PET) | (43) (SPECT) (AD < PDD) |
| Temporal lobe | (32) (PET) (58) (PET) (39) (SPECT) | (72) (SPECT) | (58) (PET) (70) (PET) (3) (SPECT) (62) (SPECT) (43) (SPECT) | (58) (PET) (74) (PET) | (70) (PET) (AD < PDD) (43) (SPECT) (AD < PDD) |
| Parietal lobe | (32) (PET) (58) (PET) (2) (SPECT) (43) (SPECT) | (72) (SPECT) | (58) (PET) (70) (PET) (3) (SPECT) (62) (SPECT) (26) (SPECT) (43) (SPECT) (67) (SPECT) | (58) (PET) (43) (SPECT) | (43) (SPECT) (AD < PDD) |
| Basal Ganglia | (46) (PET) (58) (PET) (43) (SPECT) | (58) (PET) | |||
| Cerebellum | (58) (PET) | (34) (PET) (PD‐MCI > controls) | (58) (PET) | ||
| Occipital lobe | (58) (PET) (2) (SPECT) | (58) (PET) (43) (SPECT) | (43) (SPECT) | (70) (PET) (AD > PDD) | |
| Brainstem | (34) (PET) (PD‐MCI > controls) | ||||
| Hippocampus | (46) (PET) |