FIG. 1.

Therapeutic effects of fetal gene therapy. (A) Growth curves of Akp^+/+ mice (n=4, dashed lines), untreated Akp^−/− mice (n=4, dotted lines), and treated Akp^−/− mice (n=9, continuous lines). (B) Survival curves of Akp^+/+ mice (n=8, dashed line), untreated Akp^−/− mice (n=4, dotted line), and treated Akp^−/− mice (n=9, continuous line). Statistical analysis revealed that the proportion of surviving treated Akp^−/− mice was significantly elevated compared with that of untreated Akp^−/− mice (*p<0.001).