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Histochemical staining for ALP activity. ALP activity is shown as purple staining. The pictures show the tibial bones of 14-day-old (A) and 56-day-old (B) Akp+/+ mice, a 10-day-old untreated Akp−/− mouse (C), and 14-day-old (D) and 56-day-old (E) treated Akp−/− mice. Scale bars: 250 μm. Color images available online at www.liebertonline.com/hum
