FIG. 3.
Increased rhodopsin protein in P23H transgenic eyes injected with AAV-RS301. Four P23H transgenic mice injected with AAV-RS301 in right (R) eyes and uninjected in their left (L) eyes were analyzed by immunoblot. (A) Image of anti-rhodopsin staining using C-terminal specific antibody 1D4. Protein levels were normalized to β-actin protein from the same eye. (B) Quantification of image (A), demonstrating increased RHO protein content in injected right eyes (open columns) compared with uninjected left eyes (solid columns) (n=4; *p<0.05).
