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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Reprod Toxicol. 2012 Jan 18;33(3):322–330. doi: 10.1016/j.reprotox.2012.01.001

Fig. 3. The broad ALDH inhibitor, cyanamide, impaired follicular development in eCG-primed mice.

Fig. 3

(A) Cyanamide induced apoptosis in granulosa cells as detected by TUNEL assay

(B) The expression genes known to be markers of granulosa cell differentiation and follicular development, *; Significant differences were observed as compared with those in granulosa cells recovered from mice coinjected with eCG and cyanamide (P<0.05). Values are mean +/−SEM of three replicates. immature: immature mice before eCG priming, control: 48 hr after eCG priming, cyanamide: coinjection with eCG and 15 mg/kg of cyanamide for 48 hr