Table 1.
Candidate genes for OMIM diseases with a mapped locus but no known associated gene(s)
| MIM# | Disorder Name | Candidate Gene |
|---|---|---|
| 131400 | EOSINOPHILIA, FAMILIAL | IL5 |
| 300062 | MENTAL RETARDATION, X-LINKED 14 | TIMP1 |
| 221820 | GLIOSIS, FAMILIAL PROGRESSIVE SUBCORTICAL | GFAP |
| 159555 | MYELOID/LYMPHOID OR MIXED LINEAGE LEUKEMIA | MLL |
| 178300 | PTOSIS, HEREDITARY CONGENITAL 1 | ARTN |
| 156232 | MESOMELIC DYSPLASIA, KANTAPUTRA TYPE | HOXD11 |
| 156232 | MESOMELIC DYSPLASIA, KANTAPUTRA TYPE | HOXD13 |
| 600231 | PALMOPLANTAR KERATODERMA, BOTHNIAN TYPE | PTGES3 |
| 161950 | IGA NEPHROPATHY 1 | SGK1 |
| 105550 | AMYOTROPHIC LATERAL SCLEROSIS AND/OR FRONTOTEMPORAL DEMENTIA 1 | AGTPBP1 |
| 126900 | DUPUYTREN CONTRACTUREDUPUYTREN CONTRACTURE 1, INCLUDED | SALL1 |
| 102300 | RESTLESS LEGS SYNDROME, SUSCEPTIBILITY TO, 1 | KCNC2 |
| 153600 | MACROGLOBULINEMIA, WALDENSTROM, SUSCEPTIBILITY TO, 1 | NFKBIE |
| 310460 | MYOPIA 1 | OPN1LW |
| 601941 | DIABETES MELLITUS, INSULIN-DEPENDENT, 6 | MC4R |
| 607317 | SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 4 | UBE4B |
| 603116 | CDAGS SYNDROME | MN1 |
| 609306 | SPINOCEREBELLAR ATAXIA 26 | CACNA1A |
| 313850 | THORACOABDOMINAL SYNDROME | GPC3 |
| 129900 | ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME1 | DLX5 |
| 145410 | OPITZ GBBB SYNDROME, AUTOSOMAL DOMINANT HYPERTELORISM WITH ESOPHAGEAL ABNORMALITY AND HYPOSPADIAS G SYNDROME HYPOSPADIAS-DYSPHAGIA SYNDROME OPITZ-FRIAS SYNDROME OPITZ-G SYNDROME, TYPE II TELECANTHUS W | TBX1 |
| 602483 | AURICULOCONDYLAR SYNDROME | LMNA |
| 149000 | KLIPPEL-TRENAUNAY-WEBER SYNDROME | GDF6 |
| 300652 | ANGIOMA SERPIGINOSUM, X-LINKED | EBP |
| 247200 | MILLER-DIEKER LISSENCEPHALY SYNDROME MILLER-DIEKER SYNDROME CHROMOSOME REGION, INCLUDED | HIC1 |
| 144120 | HYPERIMMUNOGLOBULIN G1(A1) SYNDROMEIMMUNOGLOBULIN HEAVY CHAIN REGULATOR, INCLUDED | KIAA1409 |
| 609625 | CHROMOSOME 10Q26 DELETION SYNDROME | FGFR2 |
| 109350 | GASTROESOPHAGEAL REFLUX | OLFM4 |
| 607498 | MIGRAINE WITH OR WITHOUT AURA, SUSCEPTIBILITY TO, 3 | POLH |
| 607516 | MIGRAINE WITH OR WITHOUT AURA, SUSCEPTIBILITY TO, 6 | TROVE2 |
| 607516 | MIGRAINE WITH OR WITHOUT AURA, SUSCEPTIBILITY TO, 6 | TROVE2 |
| 613096 | SPASTIC PARAPLEGIA 36, AUTOSOMAL DOMINANT; SPG36 | TRPV4 |
| 300125 | MIGRAINE, FAMILIAL TYPICAL, SUSCEPTIBILITY TO, 2 | OPN1LW |
| 148500 | TYLOSIS WITH ESOPHAGEAL CANCER | EVPL |
| 161550 | NASOPHARYNGEAL CARCINOMA | CDKN1A |
| 601846 | VACUOLAR NEUROMYOPATHY | CNN1 |
| 309605 | MILES-CARPENTER X-LINKED MENTAL RETARDATION SYNDROME | EFNB1 |
| 142470 | FETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 2 | L3MBTL3 |
| 166760 | OTITIS MEDIA, SUSCEPTIBILITY TO | CUZD1 |
The candidates shown appear in the top 10 hits by OWLSim using the avgIC metric.