Figure 3. Nuclear contribution to deformation (NCD) in aspirated stem cells is a quantitative measure of how the cell deforms as a unified structure.
(A) Black points in plots of NCD versus time represent CD34+ cells and white dots represent MSCs. Error bars are SEM. (B) Average values of NCD for each cell type show that the nucleus of CD34+ cells contributes more to cell deformation, less in MSCs, but not at all in PSCs, where NCD is always above 1 due to absence of nuclear mobility during aspiration. (p-value < 10−5 between cell types).