Figure 6.
Reduced post-MI fibrosis in MyD88−/− hearts. After MI (3 weeks) WT and MyD88−/− multiple heart sections were obtained spanning apical, middle and basal region (A). Sections were stained with Masson’s trichrome and collagen staining (blue) was isolated from the total staining in these images (B). Fibrosis was determined as percentage of the blue staining (collagen) of the total staining (blue+red). Average values from WT (60 sections) and MyD88−/− (45 sections) were determined that showed significant reduction in fibrosis in MyD88−/− (C; unpaired t-test, **P = 0.003).
