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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: J Mol Cell Cardiol. 2012 Jan 17;52(5):1074–1082. doi: 10.1016/j.yjmcc.2012.01.005

Figure 3.

Figure 3

Loss of SMN in the heart leads to activation of NADPH-oxidase. Western blot analysis of the heart extracts in SMNΔ7 mice indicate that very low levels of SMN (A) results in a significant increase in the levels of AT1R (B), Rac1 (C), P47-phox (D), Ang-II (E), and Nox2 (F) compared to wild type littermates at P9 or 14. The error bars present ±SE and P value was determined by two-tailed t test.