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The summary of our findings in 4 group of mice model system.
| Saline-infused | Prx-injected saline-infused | 5-HT-infused | Prx-injecte 5-HT-infused | |
|---|---|---|---|---|
| [5-HT] in plasma (ng/μl blood) | 0.85 ± 0.04 | 2.95 ± 0.05 | 2.74 ± 0.37 | 5.54 ± 0.16 |
| [5-HT] in platelet (ng/μl blood) | 5.15 ± 0.89 | 3.07 ± 0.09 | 5.77 ± 0.54 | 2.98 ± 0.01 |
| SERT on the plasma membrane (% of total) | 100 ± 0.8 | 95 ± 0.5 | 58 ± 5.9 | 94 ± 6 |
| 5-HT uptake rates (pmol/min/mg protein) | 0.76 ± 0.08 | 0.18 ± 0.04 | 0.29 ± 0.07 | 0.15 ± 0.06 |
