TABLE 1.

Doses Chosen for Exposures

Toxicant	Experiment 1: mixtures (mg/kg/day)	Experiment 2: sex (mg/kg/day)
PCB	0.51 mg: 1.7 μmol
	1.5 mg: 5 μmol
	3 mg: 10 μmol
	6 mg: 20 μmol	6 mg: 20 μmol
	12 mg: 40 μmol	12 mg: 40 μmol
	18 mg: 60 μmol
PBDE	0.96 mg: 1.7 μmol
	2.85 mg: 5 μmol
	5.7 mg: 10 μmol
	11.4 mg: 20 μmol	11.4 mg: 20 μmol
	22.8 mg: 40 μmol	22.8 mg: 40 μmol
	34.2 mg: 60 μmol
Mixture	0.51 mg PCBs + 0.96 mg PBDEs: 3.4 μmol
	1.5 mg PCBs + 2.85 mg PBDEs: 10 μmol
	3 mg PCBs + 5.7 mg PBDEs: 20 μmol	3 mg PCBs + 5.7 mg PBDEs: 20 μmol
	6 mg PCBs + 11.4 mg PBDEs: 40 μmol	6 mg PCBs + 11.4 mg PBDEs: 40 μmol

Note. Equimolar doses of PCBs and PBDEs were chosen for use in this study. The dose of the mixtures enabled comparison with the individual contaminants at the dose contained in the mixture and also at the total dose of the mixture. For experiment 1, there were n = 4 dams per treatment, with ∼n = 4 male pups per treatment group per analysis. For experiment 2, there were n = 5 dams per treatment and ∼n = 5 male and ∼n = 5 female pups per treatment group per analysis.