TABLE 1.
Patient description and outcomes versus candidal infection status
| Parameter | Candidal infection status | ||
|---|---|---|---|
| Definite infection (n=13) | Probable infection (n=20) | Colonization/no infection (n=46) | |
| Mean age (years) | 60±19 | 54±21 | 50±20 |
| Mean length of stay (days) | 55±50 | 76±57 | 33±29 |
| Intensive care unit stay | |||
| Number of patients | 12/13 (92%) | 14/20 (70%) | 14/26 (30%) |
| Mean length of stay (days) | 58±51 | 76±57 | 53±37 |
| Use of broad spectrum antibiotics | 12/13 (92%) | 19/20 (95%) | 23/46 (50%) |
| Use of central total parenteral nutrition | 1/13 (85%) | 6/20 (30%) | 8/46 (17%) |
| Immunocompromised | 2/13 (15%)* | 3/20 (15%)† | 13/46 (28%) |
| Treatment with amphotericin B | 9/13 (69%) | 9/20 (45%) | 3/46 (13%) |
| Renal dysfunction § | 8/13 (62%) | 8/20 (40%) | 6/46 (13%) |
| Patients who died | 6/13 (46%) | 7/20 (35%) | 11/46 (24%) |
| Number autopsied | 2/6 (33%) | 0/7 (0%) | 3/11 (27%) |
Error is represented as standard deviation around the mean.
*
Renal transplants (two);
†
Wegener’s granulomatosis (one), angioimmunoblastic lymphadenopathy (one), human immunodeficiency virus infection (one);
‡
Renal transplants (four), acquired immune deficiency syndrome (one), chronic lymphocytic leukemia (two), acute myelogenous leukemia (two), bone marrow transplants (three), systemic lupus erythematosis (one);
§
Values are for patients with mean serum creatinine levels greater than or equal to 150 mmol/L.