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. 2011 Oct 18;302(1):E134–E144. doi: 10.1152/ajpendo.00296.2011

Fig. 2.

Fig. 2.

Peripheral oxytocin reduces food intake and body weight in diet-induced obese (DIO) rats. Food intake and body weight change in rats maintained on a LFD (A, C) vs. HFD (B, C) following ip injection of vehicle or 125, 250, 500, or 1,000 μg/kg LBM dose of oxytocin administered immediately prior to dark cycle onset. D: body weight change in LFD and HFD fed rats that received ip administration of vehicle or oxytocin (1,000 μg/kg LBM) or vehicle and were pair-fed to intake of oxytocin-treated rats. Data represent means ± SE. *P < 0.05 vs. vehicle, #P < 0.05 vs. vehicle-PF.